Sancta Maria is located at Lingampally near Gachibowli, on a 5-acre eco-friendly campus with 1,70,000 sft of space. It provides for a 30:70 ratio between the built-up area and open space.

The campus is divided into two blocks. The first block houses the administrative offices and pre primary grades, an indoor soft gym, a library and an activity room for free play while the second block houses primary, middle and secondary grades. Both the blocks comprise of spacious, well lit and well furnished classrooms. Library, Visual Arts room, Music room, Dance room, Activity room, Math, ICT and Science Labs and two indoor badminton courts are housed in the second block.

Sancta Maria is also equipped with a spacious dining hall with in-house cooking facility and an infirmary managed by a trained nurse. It also offers day care facility for the children of the working parents.